Doktorand in der Arbeitsgruppe Prof. Dr. Ulrike Alexiev (TP B03)
Institut für Experimentalphysik
Fachbereich Physik
Freie Universität Berlin

Kontakt:
pierre.volz (at) fu-berlin.de

Dissertationsthema:
Fluoreszenzbasierte Charakterisierung von neuartigen Wirkstofftransportern auf molekularer, zellulärer und Gewebeebene

Erstbetreuerin: Prof. Dr. Ulrike Alexiev

Publikationen:

Volz P, Schilrreff P, Brodwolf R, Wolff C, Stellmacher J, Balke J, Morilla MJ, Zoschke C, Schäfer-Korting M, Alexiev U 2017. Pitfalls in using fluorescence tagging of nanomaterials: tecto-dendrimers in skin tissue as investigated by Cluster-FLIM. Ann NY Acad Sci 1405:202-214 DOI 10.1111/nyas.13473

Alexiev U, Volz P, Boreham A, Brodwolf R 2017. Time-resolved fluorescence microscopy (FLIM) as an analytical tool in skin nanomedicine. Accepted for publication in: Eur J Pharm Biopharm DOI 10.1016/j.ejpb.2017.02.005 (Review)

Boreham A, Volz P, Peters D, Keck CM, Alexiev U 2017. Determination of nanostructures and drug distribution in lipid nanoparticles by single molecule microscopy. Eur J Pharm Biopharm 110:31-38 DOI 10.1016/j.ejpb.2016.10.020

Zoubari G, Staufenbiel S, Volz P, Alexiev U, Bodmeier R 2017. Effect of drug solubility and lipid carrier on drug release from lipid nanoparticles for dermal delivery. Eur J Pharm Biopharm 110:39-46 DOI 10.1016/j.ejpb.2016.10.021

Löwenau LJ, Zoschke C, Brodwolf R, Volz P, Hausmann C, Wattanapitayakul S, Boreham A, Alexiev U, Schäfer-Korting M 2016. Increased permeability of reconstructed human epidermis from UVB-irradiated keratinocytes. Accepted for publication in  Eur J Pharm Biopharm, in press, DOI 10.1016/j.ejpb.2016.12.017

Zhang N, Said A, Wischke C, Kral V, Brodwolf R, Volz P, Boreham A, Gerecke C, Li W, Neffe AT, Kleuser B, Alexiev U, Lendlein A, Schäfer-Korting M 2017. Poly[acrylonitrile-co-(N-vinyl pyrrolidone)] nanoparticles - composition-dependent skin penetration enhancement of a dye probe and biocompatibility. Eur J Pharm Biopharm, in press, DOI 10.1016/j.ejpb.2016.10.019 (Epub ahead of print)

Radbruch M, Pischon H, Ostrowski A, Volz P, Brodwolf R, Neumann F, Unbehauen M, Kleuser B, Haag R, Ma N, Alexiev U, Mundhenk L, Gruber AD 2017. Dendritic core-multishell nanocarriers in murine models of healthy and atopic skin. Nanoscale Res Lett 12:64 DOI 10.1186/s11671-017-1835-0 (online publication, 12 pages)

Boreham A, Pikkemaat J, Volz P, Brodwolf R, Kuehne C, Licha K, Haag R, Dernedde J, Alexiev U 2016. Detecting and quantifying biomolecular interactions of a dendritic polyglycerol sulfate nanoparticle using fluorescence lifetime measurements. Molecules 21:22 DOI: 10.3390/molecules21010022 (epub, 13 pages)

Pischon H, Radbruch M, Ostrowski A, Volz P, Gerecke C, Unbehauen M, Hönzke S, Hedtrich S, Fluhr JW, Haag R, Kleuser B, Alexiev U, Gruber AD, Mundhenk L 2016. Stratum corneum targeting by dendritic core-multishell-nanocarriers in a mouse model of psoriasis. Nanomedicine: NBM 13:317-327 DOI 10.1016/j.nano.2016.09.004

Volz P, Krause N, Balke J, Schneider C, Walter M, Schneider F, Schlesinger R, Alexiev U 2016.Light and pH-induced changes in structure and accessibility of transmembrane helix B and its immediate environment in Channelrhodopsin-2. J Biol Chem 291:17382-17393 DOI 10.1074/jbc.M115.711200

Richter C, Schneider C, Quick MT, Volz P, Mahrwald R, Hughes J, Dick B, Alexiev U, Ernsting NP 2015. Dual-fluorescence pH probe for bio-labelling. Phys Chem Chem Phys 17:30590-30597 DOI 10.1039/c5cp05454k

Volz P, Boreham A, Wolf A, Kim T-Y, Balke J, Frombach J, Hadam S, Afraz Z, Rancan F, Blume-Peytavi U, Vogt A, Alexiev U 2015. Application of single molecule fluorescence microscopy to characterize the penetration of a large amphiphilic molecule in the stratum corneum of human skin. Int J Mol Sci 16: 6960-6977 DOI 10.3390/ijms16046960